Obagi Clenziderm

Obagi is the leading brand of medical skincare products.

The CLENZIderm M.D System is prescription-strength and designed to combat adult acne, to be applied morning and evening for best results. The system is comprised of three products, a Daily Foaming Cleanser, Pore Therapy Serum and Therapeutic Lotion. If you are prone to acne and breakouts then the CLENZIderm M.D System may help you get clear, hydrated and beautiful skin. It works to unclog pores and banish blemishes once and for all and is the only acne treatment system with a liquid form of benzoyl peroxide, making it clinically proven to visibly clear skin in as little as 2 weeks. 

Between the 3 revolutionary products, this system is capable of:

– Unclogging deep pores of bacteria, oil and dead skin cells with a salicylic acid and benzoyl peroxide combination. 

– Eliminating bacteria that irritates the skin and leads to acne breakouts with the use of novel Soluzyl Technology. 

– Rejuvenates your skin by tackling the root of the problem, leaving you feeling, younger, fresher and brimming with confidence.

These unique features set the Obagi CLENZIderm M.D. line apart from other skin systems that treat only the surface of the skin. If you are looking for a skincare regime that can help deep rooted skin problems, then the Obagi CLENZIderm M.D. system may be perfect for you.

How it works

The bacteria that causes acne (Scientifically known as P. acnes) lives deep in the pores, which means it can be difficult to reach with an every day face wash. So, Obagi created the CLENZIderm M.D. System, which contains benzoyl peroxide. This ingredient works to penetrate the deepest pores in your skin, but is still gentle on the surface.

The science behind Obagi Clenziderm

If you’re unsure of Obagi’s credibility, you won’t need to look far to find positive reviews and results backed by science. Clinical studies have shown that the Obagi CLENZIderm M.D. for normal to oily skin system significantly reduces follicular P. acnes bacteria compared to a leading BPO combination. P. acnes can live deep within your follicles and pores, using oil and skin cells to cause skin damage and inflammation. 

Reduction in follicular P. acnes was apparent immediately after a single application of CLENZIderm M.D. and sustained improvement was observed over the next eight hours. It was found that the system is clinically proven to provide fast clearance of inflammatory and non-inflammatory acne lesions for clearer skin you can see and feel day after day.

Obagi Clenziderm M.D. Results

With the Obagi CLENZIderm M.D. System, you could see visibly clearer skin in as little as 2 weeks. Results may vary from each individual and depends on the type and severity of the acne.


The CLENZIderm M.D ingredients work to eliminate bacteria at the source, meaning your skin will begin to heal and blemishes reduce in redness and size. When acclimating to the powerful prescription ingredients your skin may appear dry, however this is normal and won’t continue for more than 4 weeks.


After 1 month, breakouts will be less frequent due to the gentle exfoliating, antibacterial and oil-regulating effects of the system. Your complexion will look and feel smoother with less shine from excess oil, blackheads and pores will appear smaller in size. Particularly stubborn spots may still be active, but the majority of blemishes will have reduced visibly.

WEEKS 8-12

Your skin’s oil production will now be more regulated as new skin cells develop, breakouts continue to become even less frequent. Any blemishes left will be nearly completely healed and you should experience no more blackheads.

A Three-step system to clearer Skins

The three products of Obagi’s CLENZIderm M.D. system are specially formulated to work together to provide better pore penetration, quick reduction in acne-causing bacteria and visible acne reduction in as little as 2 weeks. These three products and their mechanisms of action are described: 

1. Obagi CLENZIderm M.D. Daily Care Foaming Cleanser (4 fl. oz.)

This product, as well as Obagi Pore Therapy, contain 2% salicylic acid. This oil soluble compound penetrates deep into your pores, gently washing away and removing dead skin cells, as well as restoring the skin’s natural oils. Targeting blackheads and whiteheads as well as acne, the cleanser also contains soothing menthol that cools and calms any skin irritation. Overall your skin will be left feeling cleaner, clearer and healthier. This product is designed to be applied first in the triple mechanistic system that is Obagi Clenziderm M.D. To apply, dispenses a 20p sized amount and massage into the face using warm water before rinsing and patting dry. After 10 to 15 minutes, you can apply the next product in the system.


2. Obagi CLENZIderm M.D. Pore Therapy (5 fl. oz.)

Working with a similar mechanism of action to the Daily Foaming Cleanser, this therapy cleans deep within the pores to clear skin with the aid of salicylic acid. By unclogging the pores and cleaning away dead skin cells, this product not only builds upon the cleansing action of the cleanser, it also prepares the skin so it is ready to deeply absorb the liquid serum of the third product in the system that targets acne at its source. As the second product in the Obagi CLENZIderm system, application should occur after the use of the cleanser. Saturate a cotton ball or pad and then cover the acne affected area of your face 1 to 3 times a day. Always start with one daily application to ensure your facial skin does not become dry.

3. Obagi CLENZIderm M.D. Therapeutic Lotion (1.6 fl. oz.)

This product is specially formulated with 5% benzoyl peroxide, which works its way deep down into the follicles beneath the skin where acne begins. The Therapeutic Lotion quickly clears acne and prevents new breakouts from occurring. Solubilized 5% benzoyl peroxide significantly reduces acne-causing bacteria such as P. acnes, leaving your skin purified and clear. This clever product also works to reduce future acne breakouts as well as tackling immediate blemishes. Benzoyl peroxide works by drying the conditions in which acne causing bacteria thrive. Due to this mechanism of action, it is best to begin with only one application (that covers the entire affected area of the face) daily and then increase frequency up to 3 times daily if needed. It is also recommended to wash hands after use as this product can bleach fabrics. Finally, ensure sunscreen is worn after applying this product if your skin will be exposed to the sun.